DDG 4.Nc3 Bb4

Most lines after 4...Bb4 transpose to the 4...Nf6 5.f3 Bb4 variation, so here are only considered lines where Nf6 is deferred. White often tends to castle queenside in these lines.
W

5.Qa4+!

5.Qa4+! used to be considered the best. The chief idea is to prevent Black from playing c5; sometimes White also intends to castle queenside. It is useful to study how this differs from 6.Qa4+ in the Kmoch Variation, where f3 and Nf6 have been played.

5...Nc6

W

5.Qb3!

5.Qb3 is now my favorite.

A) 5...c5 6.a3!!

B) 5...Nc6 6.Be3 Nf6 (6...f5 transposes) 7.O-O-O! [Diemer]

7.a3 Ba5 8.Rd1 Ng4 9.Bf4?! Nxd4 10.Qa4+ c6 11.b4 e5! 12.Be3 Bb6 13.c5 Bc7 14.h4 -/+, Heikkinen - Rebel Decade, 1996.

7.f3 transposes.

C) 5...Ba5 6.Be3 Ne7 7.O-O-O Bxc3 8.Qxc3 Nf5 9.Bf4 f6?! 10.h4 b6 11.f3 exf3 12.Qxf3 c6 13.Bd3!? Ne7? 14.Qg3 Na6 15.Qxg7 Rg8 16.Qxh7 Bb7 (16...Rxg2?? 17.Be4) 17.d5! cxd5 18.cxd5 Rc8+ 19.Kb1 Nc7 20.dxe6 a6 21.Qf7# 1-0, Heikkinen - Nylund, 2001.

5.Be3

I have learned to like the Be3 move in the DDG: it looks good in almost any variation. Here, for instance, it allows White to continue with Qc2 and Rd1 -- or even O-O-O!?.

5.Be3 Bxc3+

5...c5 6.Qd2 Nf6 7.dxc5 Qxd2+ 8.Kxd2 Ng4 9.a3 Bxc3+ 10.Kxc3 Nxe3 11.fxe3 a5 12.Be2 Nd7 13.Kd4 f5 14.Nh3 a4 15.g4 Ra5 16.Rhg1 Nxc5 17.Kc3 O-O 18.Rad1 draw, Jorgensen - Heikkinen, corr. 2000.

6.bxc3 Nf6

7.Qc2 (7.f3 c5 8.Qa4+ Bd7 9.Qb3 Bc6 =/+)

5.Ne2

5.Ne2 is interesting. White does not attack the pawn on e4 straight, and may even castle queenside.

5...Nc6

5...c5 6.d5 Nf6 7.a3 Bxc3+ (7...Ba5 8.b4!) 8.Nxc3 exd5 9.cxd5 Bg4 with interesting game.

5.f3?!

5.f3?!

5.Bd2?!

5.Bd2?! offers another pawn for almost nothing. White sacrifices a pawn in the DDG in order to get the half-open e-file (and possibly f-file), as well as the open diagonal b1-h7, but I have not figured out what is the idea of sacrifing this second pawn. After that, Black's plan looks too obvious: exchange pieces, and win an easy endgame. However, even Brause has played this double-sacrifice.

5...Qxd4 6.Qb3 Nc6 7.Nge2 Qe5 8.Rd1 Nf6 9.Nxe4 Bxd2+ 10.Nxd2 O-O 11.Qc3 Qxc3 12.Nxc3 Nb4, 0-1 in 66, Brause - Vampire, FICS 1996.

5...f5? seems to be losing a piece for nothing.

Various